Introduction
Welcome
Welcome to the Day 1 of the R-Mind workshop. We are very pleased to host this workshop for you.
Briefly introduce yourself
- Name
- Position (Master’s student, PhD student, Postdoc, …)
- Expectations for this course
- Something special about you so that we can remember you by!
Let’s chat a bit about OMICs…
- What is “OMICs”?
- What is a genome?
- How big is the human genome (in basepairs)?
- Around 3 billion bp (3Gbp)
- How many genes are there in the human genome?
- GENCODE v44 | Total genes=62,700 | Protein-coding genes = 19,396
- How about mouse genes?
- GENCODE M33 | Total genes=56,884 | Protein-coding genes = 21,403
- What is a transcriptome?
- What is High-throughput Sequencing (HTS) and Next-generation sequencing (NGS)?
- What are the most common HTS applications (i.e. types of sequencing)?
- What is R, and why should I care?
Additional resources
Training courses: Bioinformatics Training at the Harvard Chan Bioinformatics Core
Book: Modern Statistics for Modern Biology
CheatSheets
References
This workshop is based on the training materials from the Harvard Chan Bioinformatics Core (HBC).
Meeta Mistry, Mary Piper, Jihe Liu, & Radhika Khetani. (2021, May 24). hbctraining/DGE_workshop_salmon_online: Differential Gene Expression Workshop Lessons from HCBC (first release). Zenodo. https://doi.org/10.5281/zenodo.4783481