MitoProfiles is a research project focused on the characterization of the gene expression landscape in cancers originating from organs with inherently high metabolic rates. Funded by the Fundação para a Ciência e a Tecnologia (FCT) under the Call Advanced Computing Projects (3rd ed.) - A0 Experimental Access (round C) program, the project is led by Isabel Duarte, a researcher at the University of Algarve and a member of the Pattern Institute.
The project aims to systematically analyze mitochondrial gene expression patterns across various cancer types, particularly those arising in metabolically active organs. By leveraging publicly available transcriptomic datasets and applying bioinformatics methodologies, MitoProfiles seeks to uncover distinct mitochondrial profiles that could offer new insights into cancer metabolism and potential therapeutic targets.